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Clinical trials use it as enrollment criteria
GLP-1 receptors are very widely distributed, particularly in the brain, says Daniel Drucker, an endocrinologist at the University of Toronto, who has consulted for Novo Nordisk, Eli Lilly and other companies developing weight-loss drugs
Treat KLOW as an investigational research protocol, not a validated therapy
2) Renal diseases
The highest risk appears to be in patients with type 2 diabetes who have established diabetic retinopathy at the time of treatment initiation, particularly when aggressive glycemic targets are pursued rapidly without appropriate ophthalmologic monitoring
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