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Astrocytes and microglia as non-cell autonomous players in the pathogenesis of ALS
Twenty-five years ago, dipeptidyl peptidase-4 (DPP-4) inhibitors, commonly known as "gliptins," were introduced through virtual screening (VS) and high-throughput screening (HTS) methods (14)
The results are dramatic
Trimethylamine N-oxide and mortality risk in patients with peripheral artery disease
However, as GLP-1s originally intended to treat Type 2 diabetes (T2D) and often delivered with injection pens developed for insulin are increasingly used to treat obesity, perhaps it is worth rethinking the basis of these designs to accommodate a user group that may have different requirements
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