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Effects on Stroke Stroke is the second leading cause of death and the leading cause of disability worldwide
The agonist exclusively activates GLP-1R , driving glucose-dependent insulin secretion, delayed gastric emptying, and central satiety signaling (hypothalamic arcuate nucleus)
Insulin: too much of a good thing is bad
To view or add a comment, sign in Findings: Patients initiating semaglutide or tirzepatide had a more than 40% lower risk of hospitalization for heart failure or all-cause mortality compared with sitagliptin (a glucose-lowering drug with no effect on heart failure end points)
Bhatia, M., Ramnath, R
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