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Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

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These benefits are more important than short-term discomforts

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B12 supplementation with tirzepatide or semaglutide with B12 addresses nutrient depletion that can occur with reduced food intake and GI symptoms