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Blood 84(10):148a, 1994
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It is a complex network of interlocking genetic feedback loops involving clock genes (Clock, Bmal1), period genes (Per1, Per2, Per3), and cryptochrome genes (Cry1, Cry2)
And unlike individual anecdotes, the studies are designed to ensure that any observed benefits are due to the treatment itself and not to the placebo effect
It truly is one of the only cures we have for acne, but the risks and benefits must be carefully reviewed with your dermatologist. Basically, you might be a good candidate for Accutane if you have: severe acne, such as nodulocystic acne scarring from acne acne not responsive to other OTC and/or other more conservative prescription treatments Who shouldnt take Accutane
