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While the overall risk appears to be small, I now screen more carefully for patients with risk factors such as pre-existing optic nerve problems, glaucoma, or significant diabetic retinopathy. Recent research also connects liraglutide, the active ingredient in Saxenda and Victoza, to similar concerns

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However, some patients report difficulty sleeping during their first weeks of treatment, raising important questions about medication timing, nausea effects, and individual metabolic responses