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These mice exhibited significantly reduced skeletal muscle endurance and attenuated hyperemic response to acetylcholine, an endothelium-dependent vasodilator
J Biol Chem 264:1351923 Chen J, Stewart V, Spyrou G, Hilberg F, Wagner EF, Alt FW (1994) Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells
286 (Pt 2): 637640
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Prescription options like linaclotide and lubiprostone work through different mechanismsthey increase intestinal fluid secretion and muscle activity respectivelyand carry no contraindications with GLP-1 drugs, though they are typically reserved for severe or persistent cases
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