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Specifically, the progressive loss of behavioral control, manifested by persistent overconsumption despite adverse consequences, mirrors the sustained positive energy balance that underlies and perpetuates weight gain (O'Connor and Kenny, 2022

In this view , people become overweight more or less because their willpower is not strong enough to avoid the temptation to overeat

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(2022) GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation

These receptors include: Glucagonlike peptide1 receptor (GLP1R)