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National Library of Medicine, Feb

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GPX4 inhibition activated ferroptosis, inducing TC cell death, rapid rise in reactive oxygen species and effectively arrested cell migration in vitro

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Results Anti-nitrative effect of trisulfides as an introductory part of the study Given the potent anti-oxidative functions of GSSSG and LASSS, the first set of experiments was designed to examine if these trisulfides have potential to prevent peroxynitrite-induced nitration-dysfunction of HGF by ECL-Western blotting (see Figure 1a for the in vitro experimental design)