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4 A new safety signal flagged in TRIUMPH-4 is dysaesthesia, an abnormal skin sensation that people describe as burning, tingling, or pins-and-needles
The concern is indirect: most reported acute kidney injury events occurred in patients who had experienced nausea, vomiting, or diarrhea, leading to volume depletion
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Animal studies and clinical trials suggest that L-carnitine can improve nitrogen balance under pathological stress by enhancing protein synthesis, reducing protein breakdown, inhibiting apoptosis, and mitigating inflammatory responses (74)
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