Spiekerkoetter U, Huener G, Baykal T, Demirkol M, Duran M, Wanders R, Nezu J, Mayatepek E: Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2
Nausea affects a substantial percentage of patients, particularly during dose increases
Some of the more serious complications reported include: Bowel obstruction Gallstone attacks Pancreatitis (inflammation of the pancreas) Gastroparesis (also known as stomach paralysis) Vision problems (including sudden blindness) We've seen individuals who suffer blindness, bowel blockages that result in some sort of perforation of the bowel, sepsis and can ultimately lead to death
Pair it with a fibre gummy (or our top pick) and you have a balanced, side-effect-free foundation
That conceptual shift has profound implications for how these drugs are prescribed, evaluated, and reimbursed