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MMP-9 expression is up-regulated by macrophages and is responsible for degrading extracellular matrix proteins including collagen, which results in thinning of the plaque's fibrous cap

It is used in cell cultures and animal assays to investigate extracellular matrix remodeling , vascular signaling , and mucosal defense

Iskusnykh IY, Zakharova AA, Pathak D

Olofsson, S

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