As per the experts, oral dosage o f glutathione is 250mg twice daily empty stomach for up to 4 weeks, topical route is 2% (w/w) applied once daily for nearly 2 months, and intravenous route is 1200mg injection given weekly over 30 minutes
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Fifty units does not directly correspond to 12.5 mg at any common whole-number concentration, but at a 25 mg/mL vial (less common), 50 units would deliver exactly 12.5 mg
This allows the body to have regular hunger and satiety cycles while giving enough time to digest the food. The eat-less, more-often strategy is often recommended for people taking GLP-1s, as it can also help alleviate some of the gastrointestinal distress caused by these drugs
The 56-week estimand was assumed equal to the 52-week estimand required for modelling