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Metabolic approaches: GLP-1 Incretins (semaglutide): appetite suppression | GLP-1/GIP incretins (tirzepatide): dual hormonal agonism | 5-Amino-1MQ: NNMT enzyme inhibition a non-hormonal mechanism, directly targeting lipid and NAD+ metabolism
Conclusion The GLP-1 hormone is recognized as an effective target for the treatment of T2DM due to its multifaceted role in glucose regulation
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Additionally, it contends, The potential risk of NAION should not deter the directed use of GLP-1 RA in type 2 diabetes or in people living with obesity, at this time. 2
