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Intra-arterial delivery can increase early brain exposure but requires careful control of cell size, dose, infusion rate, and microvascular-occlusion risk [48]
Sleep and mood improvements are often reported within weeks
Mitochondria as systemic supplements of the cardio-cerebral axis As the central organelles of energy metabolism, mitochondria play a key role as systemic regulatory factors in the highly metabolically active functional axis comprising the heart and brain
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Some common causes of vitamin B12 deficiency include: Autoimmune pernicious anemia Dietary limitations, such as vegetarian or vegan diets Medical conditions that affect absorption, such as celiac and Crohns disease Identifying the specific cause of deficiency can help guide treatment and prevention strategies
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