Its very useful for managing type 2 diabetes, but it also drives weight loss
Connexins enable direct intercellular communication of metabolites, nucleotides, nutrients, and secondary messengers, regulating apoptosis, inflammation, and cellular growth, while also amplifying liver inflammation and cell death (Maes and Vinken 2017
To manage constipation, you can discuss over-the-counter stool softeners or laxatives with your doctor
Nausea (28%), diarrhea (23%), constipation (17%), and vomiting (12%) at the 12mg dose are the most commonly reported

Red flag symptoms that necessitate urgent medical review include: Symptoms of severe hypoglycaemia : confusion, difficulty speaking, loss of consciousness, seizures, or inability to self-treat low blood sugar Signs of dehydration : reduced urine output, dark-coloured urine, extreme thirst, dry mouth, sunken eyes, or rapid heartbeat Cardiovascular symptoms : chest pain, palpitations, irregular heartbeat, or shortness of breath accompanying dizziness Neurological symptoms : severe headache, visual disturbances, slurred speech, weakness, or numbness, which may indicate more serious conditions requiring immediate investigation Syncope or near-syncope : actual loss of consciousness or feeling as though one is about to faint Call 999 or go to A&E immediately if experiencing symptoms suggestive of stroke (facial weakness, arm weakness, speech problems), severe chest pain, or loss of consciousness