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For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

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These include topical creams, chemical peels, laser treatments, and sun protection

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This mechanism is supported by Pickarts foundational research on GHK-Cu and tissue remodeling, which established the peptides role in accelerating wound closure and improving the structural quality of regenerated tissue