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Investigation of chronic GAC1 treatment (20 mg/kg) demonstrated significant reductions in pulmonary inflammation and airway neutrophilia, and inhibited TNF-, IL-4, and IL-5 levels in vivo [109]

Bira Y, Bessho K, Harada H et al (2005) Transforming growth factor beta stimulates rheumatoid synovial fibroblasts via the type II receptor