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GLP-1 receptors are expressed not only in pancreatic beta cells but also in various tissues including the cardiovascular system, kidneys, and immune cells such as macrophages and lymphocytes

For a 250-pound person, this could mean losing 75 pounds, a result previously thought possible only through surgical intervention

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The 2026 breast cancer signal At the 2026 ASCO Annual Meeting, Elizabeth McDonald and colleagues at Penn Medicine presented a retrospective analysis of 111,646 women aged 45 to 80 with a BMI of 25 or higher who underwent breast imaging