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A long-acting release form of exenatide (exenatide ER, Bydureon) was approved by the FDA in 2012, becoming the first once-weekly injection of a GLP-1RA for adults with T2DM [ Table 2 ]
Jan Grtzen-Patin
1315 For example, elevated glucose concentrations activate the transcription factor carbohydrate response element-binding protein, which indirectly promotes GLP-1 secretion through regulation of target genes in intestinal L cells
However, platforms with multiple therapy verticals may allocate less specialized resources to peptide-specific monitoring, dosing protocols, and compounding oversight compared to specialists focused solely on GLP-1 optimization
