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doi:10.1056/NEJMoa1812389 16
Skin-firming treatments like massage, topicals with retinoids, or radiofrequency can assist somewhat with elasticity
Its not recommended for individuals with a personal or family history of medullary thyroid carcinoma or those with an endocrine system condition known as Multiple Endocrine Neoplasia syndrome type 2
The proposed mechanism is indirect modulation of the NO pathway rather than direct receptor agonism, though the precise molecular binding event has not been definitively characterized in peer-reviewed work
K.MallickS.MisraP.et al (2009)
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