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have developed fusion proteins composed of the GH ligand or a GHR antagonist fused to GH-binding protein (GHBP), the extracellular domain of the GHR, which is proteolytically cleaved from the receptor and exists in the circulation (Fig

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What we have is a growing body of preclinical research, early human studies, and real-world clinical observation

J Cell Physiol 165 (2), 307312