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SG is relatively long-acting with a half-life of about seven days when injected subcutaneously [91]
The early key events (cAMP signalling, insulin secretion, glucagon modulation) are measurable in cell systems
[103] These symptoms may increase fall risk and require careful evaluation in older patients
Comparators for second-line treatment consisted of canagliflozin 300 mg, empagliflozin 25 mg, dapagliflozin 10 mg, liraglutide 1.8 mg, lixisenatide 20 mcg, dulaglutide 1.5 mg, semaglutide (injectable) 1.0 mg, sulfonylurea, saxagliptin 5 mg, sitagliptin 100 mg, and linagliptin 5 mg
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