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348 A comprehensive multi-proteomic analysis of the lysine lactylome identified lactylation at 872 Kla sites on 284 proteins, predominantly associated with extracellular matrix organization and cholesterol metabolism, suggesting a correlation between lactylation and protein expression in these areas and offering insight into the potential biophysical mechanisms and impact of lactylation on tendon function
JAMA 298:11801188 Lago RM, Singh PP, Nesto RW (2007) Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials
Konopka, P., Janucik, A., Citko, A., Paszko, A., Kretowski, A
This is the basis for the rationale of LC supplementation as a therapeutic agent in sepsis [15]
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