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51-OR: A Phase 2, Randomized, Double-blind, Placebo-controlled, Dose-finding Study of BI 456906 in people with overweight/obesity

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10.1073/pnas.0708940105 60 FllerM.SopjaniM.MahmudH.LangF

While that may sound destabilizing, it points to a conformational shift in DNA duplex architecture that could facilitate transcription while preventing hardening of the genome that often accompanies age and oxidative stress [37]

For each assay, cells were plated in duplicate, with one plate containing CellTox Green Dye added according to the Express, No-Step Addition at Seeding protocol described in the CellTox Green Cytotoxicity Assay Technical Manual #TM375 (10l of CellTox Green Dye per 5ml of cells)