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Short-acting GLP-1RAs generally lower postprandial blood glucose by delaying gastric emptying time, while long-acting GLP-1RAs reduce fasting glucagon or increase fasting insulin concentration [37]

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Together, they provide patients with a medically supervised, evidence-based approach to achieving safe and lasting weight loss

When insulin signaling improves, GLP-1 can function more effectively in regulating blood sugar and appetite