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In a meta-analysis of large randomized controlled trials of GLP-1 receptor agonists in type 2 diabetes, the incidence of pulmonary fibrosis and interstitial lung disease events was lower in treated patients compared with controls, although absolute event rates were extremely low and differences did not reach statistical significance [63]
Treatment with GLP1 receptor agonists reduce serum CRP concentrations in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials
While the observed associations do not establish causality, they highlight the importance of vigilance for potential NAEs during treatment, particularly given the heterogeneous temporal patterns of onset across events
L.BonaventuraJ.LesniakW.MathewsW
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