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doi:10.1038/nchembio.212, PMID: 19718041 Zahedi Avval F, Holmgren A (2009) Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for mammalian S phase ribonucleotide reductase

HIF-1 overexpression or HO-1 agonist treatment suppresses TECs apoptosis by preventing hyperglycemia-induced mitochondrial membrane potential loss and mitochondrial fragmentation to eliminate tubular injury in DKD (108)

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Compared with creatinine, cystatin C is less influenced by age, gender, body composition, diet, or preexisting infection or cancer, so its blood levels are more consistent across different patient populations (Lassus 2012