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Examples of patient-specific factors that potentially affect treatment discontinuation and adherence are the inability or reluctance to cover drug costs, polypharmacy, changes in medical needs, language barriers leading to miscommunication with health professionals, and patient priorities
We think the most likely scenario is that interim data showed manageable tolerability, solid safety, efficacy that rivals the top drug candidates in development (around 25% weight loss), and a differentiated dosing profile (monthly or perhaps quarterly dosing)
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