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The plugin is intended for monophonic sound sources, so you do get some interesting artefacts when applying the plugin to polyphonic signals

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(2024) 67:S512

Notably, SR18 occupied the same orthosteric binding pocket on both conformers of GLP-1R, a binding site typically occupied by GLP-1 and other similar peptide mimetics, as evidenced in reported structural studies (Zhang et al., 2017