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M., Turusov V
Renal and hepatic effects: Long-term or high-dose use has been associated in case reports with adverse effects on kidney and liver function
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In addition, the brain regions involved in mediating the effects of GLP-1 on gastric emptying and satiety differ, given that the threshold dose of GLP-1 required to inhibit gastric emptying is 3,000 to 10,000 times lower than the reported threshold doses necessary to suppress feeding behavior (161)
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