[1] [2] The most plausible explanation may relate to metabolic changes associated with weight loss
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Biochem J 422:247256 Axarli I, Dhavala P, Papageorgiou AC, Labrou NE (2009b) Crystallographic and functional characterization of the fluorodifen-inducible glutathione transferase from glycine max reveals an active site topography suited for diphenylether herbicides and a novel L-site
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Furthermore, since both glucagon and GLP-1 receptors are expressed in the endocrine pancreas, GLP-1R agonists such as semaglutide may also indirectly ameliorate inflammatory injury by regulating various metabolic parameters, including glucose-dependent insulinotropic peptide (GIP), glucagon, insulin, glucose levels, and circulating free fatty acids 16,17