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Your body naturally produces GLP-1 (glucagon-like peptide-1) in your intestinal L-cells in response to food intake
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In global terms, hypothalamic pathways involved in autophagy, neurotransmitter release, cytoskeletal remodeling (RHO GTPases signaling), vesicle-mediated transport and intracellular signaling (PI3K/AKT activation) were upregulated in PWA mice treated with GLP1/E, while pathways related with vesicle transport, oxidative stress, DNA repair, metabolism and immune system were downregulated by GLP1/E treatment (Fig
There is no established direct pharmacological mechanism by which these drugs would cause respiratory symptoms, though breathing difficulties may occur indirectly through complications like severe dehydration or rare allergic reactions