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(And while slightly increasing GLP-1 levels wont result in extreme weight loss, you certainly dont want to cause them to nosedive, either.) A 2023 study found that folks with a misaligned circadian rhythm (due to factors like night shift work or insomnia) tend to have a low GLP-1 response and a high risk of insulin resistance and obesity (18)
Koschmieder S, D'Al F, Radomska H, Schneich C, Chang JS, Konopleva M, Kobayashi S, Levantini E, Suh N, Di Ruscio A, Voso MT, Watt JC, Santhanam R, Sargin B, Kantarjian H, Andreeff M , Sporn MB, Perrotti D, Berdel WE, Mller-Tidow C, Serve H, Tenen DG
Staying hydrated is critical: diarrhea increases fluid loss, so drinking water throughout the day and including electrolyte-containing beverages (coconut water, diluted sports drinks) helps prevent dehydration and supports electrolyte balance
Heres a chart showing the glucoraphanin concentration by plant age: Increasing the bioavailability of sulforaphane in cooked broccoli: Adding mustard seeds (ground brown mustard seed) increased the availability of sulforaphane from cooked broccoli by 4-fold.[ref] The study used 1g of powdered mustard seed, which would be about a half teaspoon
GLP-1 medications typically require gradual dose escalation over several weeks to months to reach therapeutic levels whilst minimising gastrointestinal side effects
