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View Study [5]"Initiation of human melanocyte culture through melanocortin-1 receptor with the use of an alpha-MSH analogue" Abdel-Malek Z, Scott MC, Suzuki I, et al., 1999 Finding: This research helped explain how MT-2 works at the cellular level, showing that melanocortin receptor activation leads to increased melanin synthesis in human melanocytes

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Similar process has been observed during chronic infections such as that caused by HIV/AIDS, where IDO enzyme was activated in tissues of infected hosts (234)