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Lower estrogen levels are frequently associated with a drop in cellular glutathione

Bevins & Besheer, 2006

All the patients fulfilled the criteria established by the American Society for Reproductive Medicine and the European Society for Human Reproduction and Embryology for diagnosing the presence of PCOS (20), and at least two of the following criteria had to be present: (a) oligomenorrhea with inter-menstrual intervals longer than 45 days, (b) clinical (acne, hirsutism) or biochemical signs of hyperandrogenism, (c) the presence of micro-polycystic ovaries at ultrasound

For example, the roles of genetic predisposition, age, and comorbidities in modulating susceptibility to neurotoxicity remain underexplored

Malabsorption can cause severe B12 deficiency