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Dietary fibers such as fructo-oligosaccharides (FOS) and galacto-oligosaccharides (GOS) can enhance the gut's production of secondary BAs and SCFAs, both of which support intestinal integrity and may reduce neuroinflammation (Salminen et al., 2021)

Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin hormone produced primarily by specialised L-cells in the distal small intestine and colon

doi:10.1016/s0006-2952(98)00094-x 54

Act D specifically inhibits ASBT, whereas CFZ is an inhibitor of OST / transporters

Another participant also described reduced psychological distress but had an increase in PHQ-9 score (P3)