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MC4R activation suppresses food intake in animal models Modulates hypothalamic energy expenditure circuits Precursor to the more selective PT-141 (bremelanotide) Non-Selective Pan-MC Agonism Receptor Selectivity Unlike its derivative PT-141, Melanotan II is a non-selective melanocortin receptor agonist that activates MC1R through MC5R with varying affinities
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This means you feel full for longer after eating, which can help reduce food intake and support weight loss efforts
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![PDF] The Effects of Dual GLP-1/GIP Receptor Agonism on Glucagon Secretion—A Review](https://figures.semanticscholar.org/0fd860de34d08549f35b05af15ce08d651210045/4-Figure1-1.png)
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