Loss of muscle mass, decreased bone growth, and the risks for cognitive deficiencies become higher
However, administration of corticosterone along with Withanolide Aduring exposure to hypobaric hypoxia significantly reduced the expression of Nrf2 as well as -GCLC in hippocampal region compared to hypoxic group treated with withanolide A only
One of the strategies to cope with As stress is the synthesis of phytochelatins (PCs), which are low molecular weight cysteine-rich peptides that can bind and sequester As in plant cells 5

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