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Una vez al da es comn para dosis ms bajas y bienestar general, mientras que dos veces al da (dividiendo la dosis total) a menudo se usa para lesiones activas y objetivos teraputicos ms dirigidos
Mechanistically, necroptosis can be triggered by a variety of extracellular and intracellular danger signals, including tumor necrosis factor- (TNF-), Fas ligand, interferons, or Toll-like receptor (TLR) ligands (133)
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