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The same promising effects on MACE were shown in the absence of DM, in patients with heart failure and obesity (SELECT trial, Lincoff et al, NEJM 2023, Deanfield et al, Lancet 2024)
The improvement of insulin sensibility has the potential to impact hormone generation and exchange processes
Wegovy requires weekly self-injections and may lead to weight regain if discontinued
It mimics a natural hormone that tells your body to produce more insulin when blood sugar is high
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