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GLP-1 RA preclinical rodent studies demonstrate an increase in thyroid C-cell neoplasm occurrence which has led to a Food and Drug Administration black box warning
It is aggressive, can invade surrounding tissue, and often metastasizes, particularly to the lungs
Expert Opin Invest Drugs 2002
Biliary and gallbladder symptoms: As a class effect observed with GLP-1 receptor agonists, there is a potential signal for gallbladder-related problems
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