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doi: 10.1590/S0100-879X2002000500011 151 OnoviranO
Regarding age-related macular degeneration (AMD), a recently published retrospective cohort study reported that GLP-1RAs were associated with reduced hazard of non-exudative and exudative AMD compared to metformin, insulin and statins (Allan et al., 2025)
Additional research has explored its prokinetic effects on gastrointestinal motility through vagal cholinergic pathways
It may also be linked to other benefits and could aid in the treatment of conditions such as depression and nonalcoholic fatty liver disease (NAFLD)
At first glucagon attracted little attention and it was not thought to have any bearing on disease
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