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Muscle mass is important to bone density because strong muscles can help stimulate and maintain bone health
Common exclusions across TRIUMPH trials include a personal or family history of medullary thyroid carcinoma or MEN syndrome type 2, prior pancreatitis, a body-weight change greater than 5 kg in the 90 days before screening, and use of weight-loss medications within 90 days
Two robust regression LME models (package(nlme)(Pinheiro et al., 2023)) were estimated for each brain region to investigate the relationship between metabolite (GSH or GABA+) levels and diagnosis group, age, and sex, accounting for the random intercept of each participant
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