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Evaluating dose- and time-dependent effects of vitamin c treatment on a Parkinsons disease fly model

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The uptake rate of Rho123 was markedly lower in the mitochondria pre-treated with colistin than that in the untreated mitochondria (slope 0.29 vs 0.57, P = 0.0005), indicating that colistin induced the depolarization of the mitochondrial inner membrane

Researchers have also investigated its contribution to experimental studies involving adipocyte biology, metabolic regulation, and intracellular energy pathways