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This, in turn, activates the PKA-Smad1/5/8 signaling cascade, ultimately upregulating hepcidin transcription (63)

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When the molar ratio of the coordinating functional groups remains constant, the absorbance observed at 584 nm for the dimer was larger than that of the monomer peptide, indicating that D-P possesses better coordination efficacy and greater stability than M-P (Fig