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Both selective AMYR agonists, and dual CTR and AMYR agonists such as sCT 5,6,7 , have demonstrated efficacy in controlling appetite and body weight, however this is not seen with a CTR-selective agonist 9

PMid:22434076

Given that age and sex ratio were unevenly distributed between the ASD and HC groups and the HC subjects were from different sources (local community, kindergarten/primary school and clinical center) in some included studies (eTable 1), we performed the stratified analyses based on the three factors

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