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Current treatment paradigms and emerging therapies for NAFLD/NASH
10.1146/annurev.nutr.012809.104810 279 TohT
By using single-cell transcriptomics and proteomics analysis, the subpopulation composition, activation status, and key secreted factors of these cells at different stages of injury can be systematically identified, and their unique roles in fibrosis regulation, angiogenesis, and extracellular matrix interactions can be clarified (250, 251)
In another study, oral supplementation of 50 mg/kg of glutathione led to an increase in the protein-bound fraction of plasma glutathione levels but did not impact the glutathione content in the blood cell or deproteinized plasma
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