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However, the enhanced benefits of combining them are still theoretical and require more research to fully understand their effects and ensure safe use

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By upregulating the receptor without increasing the ligand, penta deca peptide arginate appears to promote controlled, adaptive angiogenesis rather than uncontrolled vessel growth

Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times