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Mechanistic studies suggest DSIP may influence sleep by modulating GABAergic transmission and interacting with opioid receptor systems [10]

Either three chromatographic peaks are separately quantified against authentic reference material for each component, with response factors determined rather than assumed, or LC-MS is run with three extracted ion chromatograms so that each species is tracked on its own channel

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Meilandt WJ, Yu GQ, Chin J et al (2008) Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimers disease